Trevi Therapeutics to Report Third Quarter 2024 Financial Results and Provide a Corporate Update on November 6, 2024

TRVI 10.30.2024

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Trevi Therapeutics to Report Third Quarter 2024 Financial Results and Provide a Corporate Update on November 6, 2024

Conference call and webcast to be held at4:30 p.m. ET

NEW HAVEN, Conn.,Oct. 30, 2024/PRNewswire/ --Trevi Therapeutics, Inc.(Nasdaq: TRVI), a clinical-stage biopharmaceutical company developing the investigational therapy HaduvioTM (oral nalbuphine ER) for the treatment of chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC), today announced that senior management will host a conference call and live audio webcast onWednesday, November 6, 2024, at4:30 p.m. ET, to provide a corporate update and review the Company's financial results for the quarter endedSeptember 30, 2024.

Trevi Therapeutics, Inc. www.trevitherapeutics.com (PRNewsfoto/Trevi Therapeutics, Inc.)

To participate in the live conference call by phone, please dial (877) 870 4263 (domestic) or (412) 317 0790 (international) and ask to join the Trevi Therapeutics call. No code is necessary for access. A live audio webcast will be accessible from the 'Investors & News' section on the Company's website atwww.TreviTherapeutics.com. An archived replay of the webcast will also be available for 30 days on the Company's website following the event.

About Trevi Therapeutics, Inc.
TreviTherapeutics, Inc. is a clinical-stage biopharmaceutical company developing the investigational therapyHaduvioTM (oralnalbuphineextended-release (ER)) for the treatment of chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC).Haduvioacts on the cough reflex arc both centrally and peripherally as a kappaagonistand a mu antagonist (KAMA), which areopioidreceptors that play a key role in controlling cough hypersensitivity.Nalbuphineis not scheduled by the U.S. Drug Enforcement Agency.

The impact of chronic cough is significant and often leads to a decline in patients' social, physical, and psychological quality of life. In IPF, chronic cough may lead to worsening disease and may be associated with a higher risk of progression, death, or need for lung transplant. There are no approved therapies for the treatment of chronic cough in IPF and current treatment options provide minimal benefit to patients. Chronic cough affects up to 10% of the adult population, and Haduvio's expansion into RCC has the potential to reach patients suffering from moderate to severe refractory chronic cough. There are also no approved therapies for RCC in the U.S.

Trevi intends to propose Haduvio as the trade name for oral nalbuphine ER. Its safety and efficacy have not been evaluated by any regulatory authority.

For more information, visitwww.TreviTherapeutics.comand follow Trevi onX(formerly Twitter) andLinkedIn.

Investor Contact
KatieBarrett
TreviTherapeutics, Inc.
203-304-2499
k.barrett@trevitherapeutics.com

Media Contact
Rosalia Scampoli
914-815-1465
rscampoli@marketcompr.com

SOURCE Trevi Therapeutics, Inc.

Media Contact

Katie McManus
(203) 903-9627
k.mcmanus@trevitherapeutics.com

Trevi Therapeutics
195 Church Street, 14th Floor
New Haven, CT 06510
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