Synlogic Reports Third Quarter 2024 Financial Results

SYBX 11.12.2024

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WINCHESTER, Mass.,Nov. 12, 2024(GLOBE NEWSWIRE) --Synlogic, Inc.(Nasdaq: SYBX), a biopharmaceutical company advancing novel therapeutics to transform the care of serious diseases, today reported financial results for the third quarter 2024 and provided a corporate update.

As previously announced, the Company retainedLucid Capital Markets, LLCto act as its financial advisor to explore and evaluate strategic options for maximizing shareholder value. Potential strategic alternatives that may be explored or evaluated as part of this process include the potential for an acquisition, merger, business combination or other strategic transaction involving the Company. The Synlogic Board of Directors has not set a timetable for the conclusion of this review, nor has it made any decisions related to any further actions or potential strategic options at this time. There can be no assurance, however, that this process will result in any such transaction.

Third Quarter 2024 Financial Results

As ofSeptember 30, 2024Synlogichad cash and cash equivalents of$19.4 million.

There was no revenue for the three months endedSeptember 30, 2024, compared to$0.4 millionfor the corresponding period in 2023. Revenue for the three months endedSeptember 30, 2023was associated with the prior research collaboration with Roche.

There was a benefit of$0.7 millionrelated to research and development expenses for the three months endedSeptember 30, 2024, compared to expenses of$9.6 millionfor the corresponding period in 2023. During the three months endedSeptember 30, 2024,Synlogicreceived a refund related to the closeout of one of its clinical trials and estimates of manufacturing expenses thatSynlogicincurred were revised due to the decision to discontinue Synpheny-3, resulting in a benefit upon reversal of the accrual.

General and administrative expenses for the three months endedSeptember 30, 2024were$1.2 millioncompared to$3.4 millionfor the corresponding period in 2023.

There were restructuring charges of$0.3 millionfor the three months endedSeptember 30, 2024. The restructuring and other charges were a result of the Company’s decision inFebruary 2024to discontinue Synpheny-3, its pivotal study of labafenogene marselecobac (SYNB1934) in phenylketonuria (PKU) and evaluate strategic options for the Company. The restructuring charges were primarily related to severance expense as a result of the reduction in workforce.

For the three months endedSeptember 30, 2024,Synlogicreported a consolidated net loss of$(0.1) million, or ($0.01) per share, compared to a consolidated net loss of$(12.1) million, or$(2.57)per share, for the corresponding period in 2023.

AboutSynlogic

Synlogicis a biopharmaceutical company advancing novel therapeutics to transform the care of serious diseases in need of new treatment options.Synlogicdesigns, develops and manufactures these drug candidates, which are produced by applying precision genetic engineering to well-characterized probiotics.

Forward Looking Statements

This press release contains "forward-looking statements" that involve substantial risks and uncertainties for purposes of the safe harbor provided by the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical facts, included in this press release regarding strategy, future operations, clinical development plans, future financial position, future revenue, projected expenses, prospects, plans and objectives of management are forward-looking statements. In addition, when or if used in this press release, the words "may," "could," "should," "anticipate," "believe," "look forward," "estimate," "expect," “focused on,” "intend," "on track," "plan," "predict" and similar expressions and their variants, as they relate to Synlogic, may identify forward-looking statements. Actual results could differ materially from those contained in any forward-looking statements as a result of various factors, including: the Company may not execute on its planned exploration and evaluation of strategic alternatives; and the availability of suitable third parties with which to conduct contemplated strategic transactions; as well as those risks identified under the heading "Risk Factors" in Synlogic's filings with the U.S. Securities and Exchange Commission. The forward-looking statements contained in this press release reflect Synlogic's current views with respect to future events. Synlogic anticipates that subsequent events and developments will cause its views to change. However, while Synlogic may elect to update these forward-looking statements in the future, Synlogic specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Synlogic's view as of any date subsequent to the date hereof.

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Contact:info@synlogictx.com

Synlogic, Inc.Condensed Consolidated Statements of Operations(unaudited)
(in thousands, except share and per share data)For the Three Months EndedSeptember 30For the Nine Months EndedSeptember 30
2024202320242023
Revenue$—$393$8$602
Operating expenses
Research and development(713)9,6169,16433,831
General and administrative1,1653,4005,22811,291
Restructuring and other charges296—24,790—
Total operating expenses74813,01639,18245,122
Loss from operations(748)(12,623)(39,174)(44,520)
Total other income, net63154816,5341,784
Loss before income taxes(117)(12,075)(22,640)(42,736)
Income tax expense—(3)(5)(12)
Net loss$(117)$(12,078)$(22,645)$(42,748)
Net loss per share - basic and diluted$(0.01)$(2.57)$(1.86)$(9.17)
Weighted-average common shares used in computing net loss per share - basic and diluted12,223,9224,699,84712,186,8304,662,444

Synlogic, Inc.Condensed Consolidated Balance Sheets(unaudited)
(in thousands, except share data)
September 30, 2024December 31, 2023
Assets
Cash, cash equivalents & marketable securities$19,389$47,746
Property and equipment, net—5,603
Other assets1,36622,201
Total assets$20,755$75,550
Liabilities and stockholders' equity
Current liabilities$7,647$30,288
Long-term liabilities—12,491
Total liabilities7,64742,779
Total stockholders' equity13,10832,771
Total liabilities and stockholders' equity$20,755$75,550
Common stock and common stock equivalents
Common stock11,696,1099,186,157
Common stock warrants (pre-funded)722,1832,973,183
Total common stock12,418,29212,159,340

Certain prior period amounts have been revised to correct for an immaterial error impacting previously issued financial statements, which are more fully described in our Quarterly Report on Form 10-Q for the period endedSeptember 30, 2024.

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Source: Synlogic, Inc.

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