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Cytokinetics to Participate in the 2024 Jefferies London Healthcare Conference

CYTK 11.12.2024

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Drug:unknown aficamten

Drug:unknown omecamtiv mecarbil

Drug:unknown CK-586

Drug:unknown CK-089

Diseases:obstructive hypertrophic cardiomyopathy

Diseases:non-obstructive hypertrophic cardiomyopathy

Diseases:pediatric obstructive hypertrophic cardiomyopathy

Diseases:heart failure with severely reduced ejection fraction

Diseases:heart failure with preserved ejection fraction

Diseases:muscular dystrophy

Date of Upcoming Event:2024-11-19

Name of Upcoming Event:2024 Jefferies London Healthcare Conference

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SOUTH SAN FRANCISCO, Calif.,Nov. 12, 2024(GLOBE NEWSWIRE) --Cytokinetics, Incorporated(Nasdaq: CYTK) today announced that the Company is scheduled to participate in a fireside chat at the 2024Jefferies London Healthcare ConferenceonTuesday, November 19, 2024at4:00 PMGreenwich Mean Time atThe Waldorf Hilton HotelinLondon, England.

Interested parties may access the live webcast of the fireside chat by visiting the Investors & Media section of theCytokineticswebsite athttp://www.cytokinetics.com. The webcast replay will be archived on theCytokineticswebsite for 90 days following the conclusion of the event.

AboutCytokinetics

Cytokineticsis a late-stage, specialty cardiovascular biopharmaceutical company focused on discovering, developing and commercializing muscle biology-directed drug candidates as potential treatments for debilitating diseases in which cardiac muscle performance is compromised. As a leader in muscle biology and the mechanics of muscle performance, the company is developing small molecule drug candidates specifically engineered to impact myocardial muscle function and contractility. Following positive results from SEQUOIA-HCM, the pivotal Phase 3 clinical trial evaluatingaficamten,a next-in-class cardiac myosin inhibitor, in obstructive hypertrophic cardiomyopathy (HCM),Cytokineticssubmitted an NDA foraficamtento theU.S. Food & Drug Administrationand is progressing regulatory submissions foraficamtenfor the treatment of obstructive HCM inEurope.Aficamtenis also currently being evaluated in MAPLE-HCM, a Phase 3 clinical trial ofaficamtenas monotherapy compared to metoprolol as monotherapy in patients with obstructive HCM, ACACIA-HCM, a Phase 3 clinical trial ofaficamtenin patients with non-obstructive HCM, CEDAR-HCM, a clinical trial ofaficamtenin a pediatric population with obstructive HCM, and FOREST-HCM, an open-label extension clinical study ofaficamtenin patients with HCM.Cytokineticsis also developingomecamtiv mecarbil, a cardiac muscle activator, in patients with heart failure with severely reduced ejection fraction (HFrEF), CK-586, a cardiac myosin inhibitor with a mechanism of action distinct fromaficamtenfor the potential treatment of heart failure with preserved ejection fraction (HFpEF), and CK-089, a fast skeletal muscle troponin activator (FSTA) with potential therapeutic application to a specific type of muscular dystrophy and other conditions of impaired muscle function.

For additional information aboutCytokinetics, visitwww.cytokinetics.comand follow us onX,LinkedIn,FacebookandYouTube.

Forward-Looking Statements

This press release contains forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995 (the "Act").Cytokineticsdisclaims any intent or obligation to update these forward-looking statements and claims the protection of the Act's Safe Harbor for forward-looking statements. Examples of such statements include, but are not limited to, statements relating toCytokinetics'and its partners' research and development activities of Cytokinetics’ product candidates. Such statements are based on management's current expectations, but actual results may differ materially due to various risks and uncertainties, including, but not limited to the risks related toCytokinetics'business outlined inCytokinetics'filings with theSecurities and Exchange Commission. Forward-looking statements are not guarantees of future performance, andCytokinetics'actual results of operations, financial condition and liquidity, and the development of the industry in which it operates, may differ materially from the forward-looking statements contained in this press release. Any forward-looking statements thatCytokineticsmakes in this press release speak only as of the date of this press release.Cytokineticsassumes no obligation to update its forward-looking statements whether as a result of new information, future events or otherwise, after the date of this press release.

CYTOKINETICS® and theCYTOKINETICSand C-shaped logo are registered trademarks ofCytokineticsin theU.S.and certain other countries.

Contact:CytokineticsDiane WeiserSenior Vice President, Corporate Affairs(415) 290-7757

Source: Cytokinetics, Incorporated

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